https://www.selleckchem.com/products/sch-900776.html ); (3) comparison of design variant performance (area under the ROC curve, mean square error, etc.); and (4) selection of the optimal design variants and their calibration for each outcome. RESULTS Over 2009-2014, 5225 cases of ALI, 354 109 MI, 12 633 AKI, and 156 057 UGIB were identified using specific definitions. The number of detectable drugs ranged from 61 for MI to 25 for ALI. Design variants generated more than 50 000 points estimates. Results by outcome will be published in forthcoming papers. CONCLUSIONS ALCAPONE has shown the interest of the empirical assessment of pharmacoepidemiological approaches for drug safety alert generation and may encourage other researchers to do the same in other databases. © 2020 John Wiley & Sons Ltd.PURPOSE The purpose of this study was to obtain information about the resident selection and match process that occurred for the Commission on Dental Accreditation (CODA) accredited Advanced Education in Prosthodontics program in North America from the program directors' perspective, after the first year of implementation. MATERIALS AND METHODS The list of Advanced Education in Prosthodontics program in CODA-accredited North American institutions was obtained from the ACP central office and the directors of each programs was identified. The surveys were distributed to 48 program directors online and results were compiled. RESULTS Out of 48 programs, 43 directors responded to and completed the survey (90.0%) where 35 programs participated in match process, 5 did not, and 3 were omitted due to incomplete surveys. While the majority of programs did not see any changes in their applicant pool or their quality, 10 programs (25.0%) observed a number of increases in the application and 13 programs (32.5%) observed an increase in the quality of the applications. Among the 35 programs that participated in Match process, the main reasons for their participation was "fairness" (48.2%), "di