https://www.selleckchem.com/products/way-316606.html A median age for CF diagnosis was 11 days old (range 0 days-16 years). The most common genotype (49.6%) was homozygous for ΔF508 mutation. Fifty-five (41.4%) patients had 1-2 episodes of AOM, and 15 (11.3%) were severely affected (i.e. ≥3 episodes/6 months or ≥4 episodes/year). COME was diagnosed in 4 (3.0%) of the patients. Twelve (9.0%) patients had tympanostomy tubes at least once, including 3 patients with multiple sets of tubes. Having at least one AOM episode was not predicted by genetic mutation groups, BMI, age at diagnosis, or comorbidities, p > .05. CONCLUSIONS The time-honored adage of CF protecting against otitis media is no longer true and pediatric otolaryngologists must now prioritize the management of middle ear disease as highly as sino-nasal and pulmonary disease. Future study into mechanisms explaining the change is needed. Studies on scene perception have shown that the rapid extraction of low spatial frequencies (LSF) allows a coarse parsing of the scene, prior to the analysis of high spatial frequencies (HSF) containing details. Many studies suggest that scene gist recognition can be achieved with only the low resolution of peripheral vision. Our study investigated the advantage of peripheral vision on central vision during a scene categorization task (indoor vs. outdoor). In Experiment 1, we used large scene photographs from which we built one central disk and four circular rings of different eccentricities. The central disk either contained or not an object semantically related to the scene category. Results showed better categorization performances for the peripheral rings, despite the presence of an object in central vision that was semantically related to the scene category that significantly improved categorization performances. In Experiment 2, the central disk and rings were assembled from Central to Peripheral vision (CtP sequence) or from Peripheral to Central vision (PtC sequence).