https://www.selleckchem.com/products/eg-011.html 93 [95%CI 1.49-2.38, p-value <0.001] and 1.81 [95%CI 1.21-2.41, p-value <0.001], respectively. Furthermore, levels of cholesterol were greater in tubes containing 2.5% sodium bicarbonate solution after digestion than in tubes containing docusate sodium; 11 mg/dl [95%CI 1.47-24.14, p-value = 0.083]. Both spectrophotometric and cholesterol level assessments suggest that 2.5% sodium bicarbonate has a higher cerumenolytic effect than docusate sodium. In other words, cerumen can be dissolved in 2.5% sodium bicarbonate much better than docusate sodium in a time-dependent manner. Both spectrophotometric and cholesterol level assessments suggest that 2.5% sodium bicarbonate has a higher cerumenolytic effect than docusate sodium. In other words, cerumen can be dissolved in 2.5% sodium bicarbonate much better than docusate sodium in a time-dependent manner. Tuberculosis (TB) of the middle ear cleft (MEC) is a rare extra-pulmonary manifestation. Signs and symptoms of tuberculous otitis media are indistinguishable from that of non-tuberculous otitis media making early diagnosis difficult. To study the clinical presentations, complications and effective diagnostic modalities in tuberculosis of middle ear cleft. We retrospectively studied 10 patients diagnosed with chronic otitis media, unresponsive to 2 months conventional treatment. Pure tone audiogram, High resolution computed tomography (HRCT) of temporal bone, and AFB staining of ear discharge were done. All patients underwent mastoid surgery. AFB staining and histopathological examination of granulation tissue removed from the middle ear and mastoid were also done. Clinical findings were mastoid swelling, facial palsy and post-aural fistula 3,4 & 2 patients respectively. All patients had persistent ear discharge and three had vertigo. Hearing loss was of moderate conductive type in five, sensorineural type in three and mixed type in two. HRCT of temporal bone revealed soft ti