https://www.selleckchem.com/products/resatorvid.html CRISPR/Cas9 gene editing technology has taken the scientific community by storm since its development in 2012. First discovered in 1987, CRISPR/Cas systems act as an adaptive immune response in archaea and bacteria that defends against invading bacteriophages and plasmids. CRISPR/Cas9 gene editing technology modifies this immune response to function in eukaryotic cells as a highly specific, RNA-guided complex that can edit almost any genetic target. This technology has applications in all biological fields, including plant pathology. However, examples of its use in forest pathology are essentially nonexistent. The aim of this review is to give researchers a deeper understanding of the native CRISPR/Cas systems and how they were adapted into the CRISPR/Cas9 technology used today in plant pathology-this information is crucial for researchers aiming to use this technology in the pathosystems they study. We review the current applications of CRISPR/Cas9 in plant pathology and propose future directions for research in forest pathosystems where this technology is currently underutilized.Root-knot nematodes (RKNs), Meloidogyne spp., are sedentary endoparasites that negatively affect almost every crop in the world. Current management practices are not enough to completely control RKN. Application of certain chemicals is also being further limited in recent years. It is therefore crucial to develop additional control strategies through the application of environmentally benign methods. There has been much research performed around the world on the topic, leading to useful outcomes and interesting findings capable of improving farmers' income. It is important to have dependable resources gathering the data produced to facilitate future research. This review discusses recent findings on the application of environmentally benign treatments to control RKN between 2015 and April 2020. A variety of biological control strategies,