https://www.selleckchem.com/products/Raltitrexed.html The size of Herafill granules has significant impact on the development of periosteal-like structures around the defect using Masquelet's induced membrane technique. Small granules show significantly increased regrowth of periosteum and improved bone formation adjacent to the induced membrane. The size of Herafill® granules has significant impact on the development of periosteal-like structures around the defect using Masquelet's induced membrane technique. Small granules show significantly increased regrowth of periosteum and improved bone formation adjacent to the induced membrane. To improve quality of trauma room management, intra- and inter-hospital benchmarking are important tools. However, primary data quality is crucial for benchmarking reliability. In this study, we analyzed the effect of a medical documentation assistant on documentation completeness in trauma room management in comparison to documentation by physicians involved in direct patient treatment. We included all patients treated in the trauma room from 2016/01/01 to 2016/12/31 that were documented with the trauma module of the German Emergency Department Medical Record V2015.1. We divided the data into documentation by medical documentation assistant (DA, 0700 to 1700), physician in daytime (PD, 0700 to 1700), and physician at night (PN, 1700 to 0700). Data were analyzed for completeness (primary outcome parameter) as well as diagnostic intervals. There was a significant increase in complete recorded data for DA (74.5%; IQR 14.5%) compared to PD (26.9%; IQR 18.7%; p < 0.001) and PN (30.8%; IQR 18.9; p < 0.001). The time to whole-body computed tomography (WBCT) significantly decreased for DA (19min; IQR 8.3) compared to PD (24min; IQR 12.8; p = 0.007) or PN (24.5min; IQR 10.0; p = 0.001). In presence of a qualified medical documentation assistant, data completeness and time to WBCT improved significantly. Therefore, utilizing a professional DA