https://www.selleckchem.com/products/palazestrant.html Acute toxoplasmosis (AT) which is caused by ( ) leads to induction of pro-inflammatory and/or oxidative stress changes through activation of host immune response. Therefore, the endeavor of the present study was to assess endothelial dysfunction(ED) and oxidative stress in patients with acute toxoplasmosis. This study involved 21 patients with AT compared with 20 healthy controls. Serum immunoglobulin levels [IgG], IgM, IgA), Interleukin-6 (IL-6), endothelin-1 (ET-1), and human malondialdehyde (MDA) serum levels were evaluated. IgM, IgG, and IgA levels were high patients with AT as compared with the control ( < 0.01). IL-6, MDA, and ET-1 serum levels were high in patients with AT compared with control ( < 0.01). In patients with AT, IgM serum level was significantly correlated with other immunoglobulin, and with the biomarker of oxidative stress, lipid peroxidation, and ED ( = 0.0001). AT is linked with oxidative stress and pro-inflammatory changes which together provoke ED. AT is linked with oxidative stress and pro-inflammatory changes which together provoke ED. This study aimed to identify asymptomatic malaria carriers and study the differences in local and migrant population in Mangalore. This study was conducted using two-stage cluster sampling. In the first stage, wards were randomly selected. The sample size for each cluster (wards) was determined using the probability proportionate to size method. In the second stage, required number of households was selected using a simple random sampling technique from each cluster. From the selected clusters, samples from 140 participants were collected. Of the 140 cases, 106 (75.7%) were male and 34 (24.3%) were female. Six cases (4.3%) of the 140 cases were positive for malarial parasites, of which gametocytes of were noted in three cases and schizonts of in three cases. From the total number of cases, 56 (40%) constituted the migrant population and the remaining 8