https://www.selleckchem.com/products/bersacapavir.html Article title and bibliographic information Periodontal condition of patients with thalassemia major A systematic review and meta-analysis. Akcalı A, Yıldız MS, Akcalı Z, Huck O, Friedmann A. Arch Oral Biol 2019;102113-21. Source of funding Information is not available and the authors state that no specific funding was available for this study. Type of study/design Systematic review with meta-analysis of data.Article title and bibliographic information The effectiveness of Alt-RAMEC combined with maxillary protraction in the treatment of patients with a class III malocclusion a systematic review and meta-analysis, Mohammed Almuzian, Elise McConnell, M. Ali Darendeliler, Fahad Alharbi & Hisham Mohammed. J Orthod 2018;45(4);250-9. Source of funding No financial support was reported. Type of study/design Systematic review.Background It has been shown that the risk of developing oral cancer is closely related to the intensity and duration of exposure to alcohol and tobacco. Even so, the use of mouthwashes with alcohol in their compositions and the increased risk of oral cancer has been a source of controversy for decades. Objective This study proposes a systematic review and a meta-analysis of the literature, to assess the possible relationship between the use of mouthwashes with alcohol and the development of oral and pharyngeal cancers. Materials and methods A systematic search was done using the Medline and PubMed databases. Exclusion criteria were as follows articles published in languages other than English or Spanish, systematic reviews, and expert opinions. No limitations were used for publication date. Results A total of 14 articles were obtained, 11 case-control studies and 3 clinical trials. Three case-control studies found no statistically significant evidence between the relationship of mouthwash use and oral cancer and the remaining 8 case-control studies found statistically significant evidence. The 3