What is a Microfluidic Jet High-Pressure Homogenizer (HPH)?
A Microfluidic Jet High-Pressure Homogenizer (HPH), like the NanoGenizer, is an advanced device used to achieve precise nanomaterial preparation. It works by forcing liquids through a small orifice at ultra-high pressures of up to 60,****psi, producing highly uniform suspensions and emulsions at the nanoscale. This process is crucial for various industries including pharmaceuticals, biotechnology, and nanotechnology, where uniform particle size and consistency are critical.

How Does a Microfluidic High-Pressure Homogenizer Work?
The working principle of Microfluidic High-Pressure Homogenizers relies on subjecting samples to ultra-high pressure through a microfluidic jet system. This system includes a specialized diamond interaction chamber, where the sample is pressurized and accelerated to speeds exceeding 1,****m/s, faster than the speed of sound (340 m/s).

As the sample passes through the diamond micro-channels, it experiences:

High-frequency shearing
Cavitation
High-energy impacts
Rapid pressure drops
These forces result in particle size reduction at the nanoscale, creating a uniform and stable mixture. The use of fixed Y- or Z-shaped diamond micro-channels ensures repeatability and precision in the process, making it highly reliable for industries requiring nanoscale homogenization.

Benefits of High-Pressure Homogenizers Over Conventional Homogenizers
Compared to conventional homogenizers, which operate at pressures up to 15,****psi, high-pressure homogenizers reach pressures as high as 60,****psi, providing better cell disruption and particle size reduction. These machines are essential for industries like pharmaceuticals, where producing highly uniform particle sizes is necessary for drug formulation and delivery.

The NanoGenizer microfluidic high-pressure homogenizer is particularly valuable for handling rare and valuable samples due to its low dead volume and continuous flow capabilities of up to 120 mL/min. It’s widely recognized for its high shear rates, scalability, and consistency, making it ideal for lab-scale and industrial applications.

Key Features of the NanoGenizer Microfluidic Jet High-Pressure Homogenizer
Ultra-high pressure capability up to 60,****psi
Consistent particle size reduction
Precise control with diamond micro-channels
Scalable from lab to production
Continuous flow processing of up to 120 mL/min
Minimal dead volume for rare and valuable samples
This cutting-edge technology is used in a variety of nanotechnology and pharmaceutical applications, including drug delivery, emulsification, and nanoparticle formulation.

Genizer offers top-tier high-pressure homogenizers like the NanoGenizer, which utilize microfluidic jet technology to ensure superior homogenization and nanomaterial processing results.

https://www.genizer.com/art/high-pressure-homogenizer-introduction_a0049.html