https://www.selleckchem.com/products/BMS-790052.html The issue of reuse of metal alloys in dentistry raises debatable questions about their impact on the human body. The aim of the study was the evaluation of the biocompatibility of metal structures of dentures made from cobalt-chromium and nickelchromium alloys Remanium GM 700 and Remanium CSe after repeated vacuum remelting. Clinical study and treatment with fixed prostheses based on Remanium GM 700 and Remanium CSe were performed among 120 patients aged 25-60 years. The biocompatibility of the above-mentioned denture designs with oral tissues was studied. Prostheses made from Remanium GM 700 and Remanium CSe alloys are biologically indifferent, which is confirmed by the indicators of alkaline and acid phosphatase activity within the physiological norm. Regardless of the number of remelts, these alloys do not cause dysbacteriosis. The obtained results do not depend on the terms of observation, which indicates the safe use of remolten alloys for dental prosthetics. The investigated alloys are biocompatible and can be used for the manufacture of solid structures of dentures. The investigated alloys are biocompatible and can be used for the manufacture of solid structures of dentures. The aim of the research involved determination of catalase and superoxide dismutase content in oral fluid of patients exposed to occupational vibration depending upon their dental status. The assessment of dental status (DS) and superoxide dismutase (SOD) and catalase (CAT) content in oral fluid (OF) was performed in three groups of patients control group (n0=129) included the persons exposed to occupational vibration and whose results of combined medical examination excluded the presence of vibration disease (VD); the second (n1=63 patients with VD stage I) and the third (n1=66 patients with VD stage II) groups consisted of the patients, who underwent treatment at the clinical department of the Research Institute of Occupational Hygien