https://www.selleckchem.com/products/bmn-673.html Then there is no significant difference between DC of the three composite bulk-fill resins by (second-generation LED vs third-generation LED curing light). The second-generation LED curing light can still be used to cure bulk-fill resin composites by increasing the duration of irradiation. In the microhardness test, there was a significant difference in the Filtek™ Bulk-Fill Posterior Restorative resin composites. In the microhardness test, there was a significant difference in the Filtek™ Bulk-Fill Posterior Restorative resin composites. This clinical study aimed to evaluate the efficacy of a toothpaste containing a proprietary REFIX technology (Regenerador + Sensitive DentalClean, Rabbit Corp) against dentin hypersensitivity. Fifty-three volunteers who fulfilled the inclusion criteria and signed the consent form were included. They were examined for dentin hypersensitivity. The participants received a 1-second blast of air, and the tooth sensitivity, from 0 to 10, was immediately evaluated using a visual analog scale (VAS). Then, the participants brushed their teeth with the multifunctional toothpaste, and dentin hypersensitivity was tested a second time using the same scale. The participants continued to use the toothpaste three times a day for 1 week, after which dentin hypersensitivity was recorded for the third time. Data were statistically analyzed using analysis of variance (ANOVA) and Tukey's test ( = 0.05). The mean patient age was 40 years, and 70% of the 53 subjects were female. There was a significant reduction in dentin hsence of pain, a desired clinical condition in patients with dentin hypersensitivity, was reached with the use of desensitizing toothpaste containing REFIX technology after 1 week of use. Such condition positively impacts quality of life, providing a healthier daily routine for patients. This study aims to evaluate and compare the efficacy of auto-control syringe (ACS) and insulin syrin