Biocomposite nanomaterials have been evolved as the new generation catalysts and therapeutic supplement in these days. Magnetically isolation has added new features to this category. This has encouraged us to synthesize a novel Ag NP adorned chitosan-alginate dual bio-polysaccharide (two of the more versatile polysaccharides) modified core-shell magnetic nanocomposite (Fe3O4/CS-Alg/Ag NPs). The material was meticulously characterized following different physicochemical techniques, such as, FT-IR, ICP-OES, FESEM, EDX, atomic mapping, TEM, VSM, XRD and XPS studies. The as synthesized material was catalytically explored in the one-pot multicomponent synthesis of biologically potent 2H-indazolo[2,1-b]phthalazine-trione derivatives involving a wide range of substrates. The reactions were ended up with excellent yields under solvent-free heating conditions. The catalyst recyclability, heterogeneity and leaching tests were performed to ensure its high stability and robustness. It could be reused as much as 10 times t result of lung protective properties of catalyst against α-Guttiferin was seen in the high dose of catalyst i.e., 4 μg. DPPH test revealed similar antioxidant potentials for catalyst and butylated hydroxytoluene. The catalyst inhibited half of the DPPH molecules in the concentration of 171 μg/mL. According to the above results, catalyst can be administrated as a lung protective drug for the treatment of lung diseases after approving in the clinical trial studies in humans.Hydrogels for complex and chronic wound dressings must be conformable, absorb and retain wound exudates and maintain hydration.  https://www.selleckchem.com/products/jib-04.html  They can incorporate and release bioactive molecules that can accelerate the healing process. Wound dressings have to be in contact with the wound and epidermis, even for long periods, without causing adverse effects. Hydrogel dressing formulations based on biopolymers derived from terrestrial or marine flora can be relatively inexpensive and well tolerated. In the present article hydrogel films composed by agarose (1.0 wt%), κ-carrageenan at three different concentrations (0.5, 1.0 and 1.5 wt%) and glycerol (3.0 wt%) were prepared without recourse to crosslinking agents, and characterized for their mechanical properties, morphology, swelling and erosion behavior. The films resulted highly elastic and able to absorb and retain large amounts of fluids without losing their integrity. One of the films was loaded with the aqueous extract from Cryphaea heteromalla (Hedw.) D. Mohr for its antioxidant properties. Absence of cytotoxicity and ability to reduce the oxidative stress were demonstrated on NIH-3T3 fibroblast cell cultures. These results encourage further biological evaluations to assess their impact on the healing process.Exopolysaccharides (EPS) from lactic acid bacteria (LAB) are much diversed in structure, composition and applications which also adding a great commercial potential due to its generally recognized as safe (GRAS) status. LAB genus such as Lactobacillus, Leuconostoc, Streptococcus, Weissella, Lactococcus are known to produce EPS. Among this genus, Weissella is enormously reported for diversity and high production of EPS with wide range of industrial applications and bio-functional properties. This review summarize in detail about the Weissella EPS from genus to functional application. Physico-chemical characterization from production, purification step to structural elucidation of Weissella EPS is comprehensively discussed along with their properties. Weissella genus has revealed various EPS with significant functional potentials, making massive application in food and pharma industries as viscosifiers, biothickener, emulsifiers and stabilizers. In addition to this, biological properties of these EPS revealed multiple health promoting properties which can be explored for further applications in food and pharmaceutical sectors.Microcrystalline cellulose (MCC) has been utilized as an adsorbent material for the removal of Pb(II) ions from aqueous solution after treatment with 1,2,3,4-butanetetracarboxylic acid (BTCA) at elevated temperature to obtain MMCC. The resulting adsorbent was characterized for point of zero point charge (pHZPC), estimation of carboxyl content, Fourier transform infrared spectroscopy (FT-IR), scan electron microscopy (SEM), and textural properties, including surface area, and subsequently utilized for the removal of Pb(II) ions from aqueous solution. The adsorption process was probed by investigating the effect of adsorbent dose, pH of solution, temperature, agitation time, and Pb(II) ion concentration. The results showed successful functionalization of MCC using BTCA, significantly improved the binding properties of the adsorbent towards Pb(II) ions. Isothermal adsorption data was analyzed using Langmuir, Freundlich and Temkin models, evaluated via nonlinear regression analysis. The maximum adsorption capacity was found to be 1155 mg/g (at pH 5 and 30 °C) from Langmuir theory, and appears independent of surface area. The Freundlich model was found to provide the best fit and the constant n was determined to be 2.69, indicating that adsorption of Pb(II) ions onto MMCC is favorable. Kinetic modelling showed good agreement for the pseudo-second order kinetic model, supporting the theory that chemisorption is involved in the adsorption process, which is promoted by a high density of active sites. Thermodynamic analysis showed that the adsorption of Pb(II) ions onto MMCC was endothermic and nonspontaneous; hence, MMCC offers an effective method of Pb(II) ion removal from aqueous solutions, with potential for water remediation processes.Researchers have looked to cartilage tissue engineering to address the lack of cartilage regenerative capability related to cartilage disease/trauma. For this, a promising approach is extrusion-based three-dimensional (3D) printing technique to deliver cells, biomaterials, and growth factors within a scaffold to the injured site. This paper evaluates the printability of chitosan scaffolds for a cartilage tissue engineering, with a focus on identifying the influence of drying technique implemented before crosslinking on the improvement of chitosan printability. First, the printability of chitosan with concentrations of 8%, 10%, and 12% (w/v) was evaluated and 10% chitosan was selected for further studies. Then, different drying methods, including air drying, warm drying, and vacuum drying followed by crosslinking, were used to study their effect on the mechanical properties of the 10% chitosan scaffolds. Our compression testing results showed the highest elastic modulus for the scaffolds crosslinked with the air-drying technique; as a major part of experiemtn, pore sizes were studies and scaffolds with smaller pore sizes showed higher elastic modulus.