https://www.selleckchem.com/products/ex229-compound-991.html The initial line of work of the HNS was modified during the implementation toward a stronger focus on involvement in health tourism-related issues. Cooperation partners and stakeholders rated this repositioning favorably. The HNS concept was successfully implemented. The realignment of HNS job specifications facilitated its local establishment. An implementation manual is intended to support the transfer of the HNS concept to other health resorts and spas. The HNS concept was successfully implemented. The realignment of HNS job specifications facilitated its local establishment. An implementation manual is intended to support the transfer of the HNS concept to other health resorts and spas. Patients with hip fractures, often of advanced age and with multimorbidity-trauma, require early surgery and interdisciplinary treatment in order to avoid complications and reduce morbidity and mortality. "Time to surgery" is a sensitive quality indicator (QI) for the treatment process, reflecting multiple factors. Due to persistently noticeable problems in relation to this QI in external inpatient quality assurance in Germany, a special need for action was identified by the Federal Joint Committee (Gemeinsamer Bundesausschuss - G-BA). Identification of methodologically particular reliable recommendations to establish structural and procedural standards to ensure adequate clinical care. Systematic international web-based research and analysis of relevant guidelines for domain 3 of the AGREE II instrument; extraction of distinct, methodologically well-founded recommendations; supplementing the guideline analysis with an assessment of regulations with structure and process requirements or criteria for quality and care standards. Out of 66 identified, context-relevant guidelines, 15 were of "high methodological quality". Out of these 15, particular reliable recommendations could be extracted-among others - regarding surgic