https://www.selleckchem.com/products/nigericin-sodium-salt.html Although it found a variance in reported patient outcomes, the review also identified an emerging body of evidence supporting the efficacy of the LP for many participants with fatigue, physical function, pain, anxiety and depression. It concludes that there is a need for more randomised controlled trials to evaluate if these positive outcomes can be replicated and generalised to larger populations. The review identified variance in the quality of studies across time; earlier studies demonstrated a lack of control groups, a lack of clarity of aspects of the methodology and potential sampling bias. Although it found a variance in reported patient outcomes, the review also identified an emerging body of evidence supporting the efficacy of the LP for many participants with fatigue, physical function, pain, anxiety and depression. It concludes that there is a need for more randomised controlled trials to evaluate if these positive outcomes can be replicated and generalised to larger populations. Anxiety may lead to negative post-surgery outcomes in patients. It is essential to find strategies to manage pre-surgery anxiety and prevent unwanted consequences in patients. Aromatherapy and music therapy can be used to help patients managing their pre-surgery anxiety. To compare the effects of Geranium aromatherapy and music therapy on the anxiety level of patients undergoing inguinal hernia surgery. This randomized clinical trial was conducted in Imam Educational Hospital in Mahabad, Iran. One hundred and fifty patients were recruited and randomly allocated to aromatherapy, music therapy, and control groups. The Spielberger State-Trait Anxiety Inventory was used to measure the patients' pre-surgery anxiety (primary outcome) before and after the intervention. Geranium essential oil and instrumental music were used in aromatherapy and music therapy groups respectively. The patients in the control group received no