https://www.selleckchem.com/products/ziritaxestat.html The Fisher exact test, chi-square test, Mann-Whitney U test, Wilcoxon test for paired samples, and sign test were applied to the data (α = 0.05). After 3 students in the control group were excluded because they received fixed orthodontic appliances, 37 students participated in the control group and 40 in the experimental group. Both groups presented a 30% reduction in PI (P less then 0.001) after the interventions. The experimental group flossed significantly more frequently (P = 0.003) than the control group. The interventions had no statistically significant effect on GBI, and there were no significant differences in toothbrushing frequency after interventions or between groups. Both approaches to oral health education-conventional and digital-had a positive impact on the reduction of the PI, and the use of a smartphone app seemed to be an effective resource for providing oral health education to students. Trial registration Registro Brasileiro de Ensaios Clinicos (ReBEC) No. U1111-1216-4770.Autism spectrum disorder is a neurodevelopmental disorder affecting communication, behavior, and socialization in a large number of children and adults. In addition to the classically considered features of autism, individuals with this disorder also often present with multiple significant medical comorbidities that affect dental treatment. This article discusses the most common of these neurologic, psychiatric, and gastrointestinal issues and explores their relevance to dental care. It is incumbent on dentists and members of the dental team to be familiar with the features and comorbidities of autism spectrum disorder and effectively use this knowledge to provide care for patients with autism.Gingival recession is a common problem that requires periodontal surgery to restore esthetics. The vestibular incision subperiosteal tunnel access (VISTA) technique is a minimally invasive recession coverage method that has gained po