https://www.selleckchem.com/products/iox1.html The present study elucidated the structures of three A-type tri- and tetrameric proanthocyanidins (PACs) isolated from Cinnamomum verum bark to the level of absolute configuration and determined their dental bioactivity using two therapeutically relevant bioassays. After selecting a PAC oligomer fraction via a biologically diverse bioassay-guided process, in tandem with centrifugal partition chromatography, phytochemical studies led to the isolation of PAC oligomers that represent the main bioactive principles of C. verum two A-type tetrameric PACs, epicatechin-(2β→O→7,4β→8)-epicatechin-(4β→6)-epicatechin-(2β→O→7,4β→8)-catechin (1) and parameritannin A1 (2), together with a trimer, cinnamtannin B1 (3). Structure determination of the underivatized proanthocyanidins utilized a combination of HRESIMS, ECD, 1D/2D NMR, and 1H iterative full spin analysis data and led to NMR-based evidence for the deduction of absolute configuration in constituent catechin and epicatechin monomeric units.In the past decade, researchers have put forth a lot of efforts to conceive a precise structural arrangement and properties of deep eutectic solvents (DESs) that provide designer pathways in order to broaden the application domain of these solvents. However, these contributions are limited to a few experimental and computational techniques. In this review, we have encompassed experimental techniques employed to establish the structure-property relationship of bulk DESs along with recent growth witnessed in this domain from a computational perspective. The nanostructuring plays an important role in various task specific applications of DESs. These solvents are found to exhibit unique heterogeneity at nanolength scales, the origin of which is unique and primarily depends on the constituent species involved. The hygroscopic nature of some DESs makes it crucial to explore the structural anatomy of hydrated DESs. Hence, this opens another subdomai