https://www.selleckchem.com/products/cp-43.html The Upper Indus Basin (UIB) is a major source of supplying water to different areas because of snow and glaciers melt and is also enduring the regional impacts of global climate change. The expected changes in temperature, precipitation and snowmelt could be reasons for further escalation of the problem. Therefore, estimation of hydrological processes is critical for UIB. The objectives of this paper were to estimate the impacts of climate change on water resources and future projection for surface water under different climatic scenarios using soil and water assessment tool (SWAT). The methodology includes (i) development of SWAT model using land cover, soil and meteorological data; (ii) calibration of the model using daily flow data from 1978 to 1993; (iii) model validation for the time 1994-2003; (iv) bias correction of regional climate model (RCM), and (v) utilization of bias-corrected RCM for future assessment under representative concentration pathways RCP4.5 and RCP8.5 for mid (2041-2070) and late centinable management of water resources in future.We propose a modelling framework for the optimal selection of crypto assets. We assume that crypto assets can be described according to two features security (technological) and stability (governance). We simulate optimal selection decisions of investors, being driven by (i) their attitudes towards assets' features, (ii) information about the adoption trends, and (iii) expected future economic benefits of adoption. Under a variety of modelling scenarios-e.g. in terms of composition of the crypto assets landscape and investors' preferences-we are able to predict the features of the assets that will be most likely adopted, which can be mapped to macro-classes of existing crypto assets (stablecoins, crypto tokens, central bank digital currencies and cryptocurrencies).Whether you believe free will exists has profound effects on your behaviour, across different levels of pr