https://www.selleckchem.com/Bcl-2.html The primary outcome contains pain at 1 month, 3 months and 6 months and hip function at 1 month, 3 months and 6 months. Secondary outcome includes the life quality, mortality rate, complications such as deep venous thrombosis, pulmonary embolism. Comparison of outcome indicators in 2 groups after conservative treatment or surgical treatment (Table). The current trial will offer better evidence for the future treatment selection for Garden 1 FNFs for patients older than 75years old. researchregistry6147. researchregistry6147. Ethylene diamine tetra-acetic acid (EDTA) is a chelating agent which attach to metals such as calcium and enables their elimination. In particular, some researchers suggest chelation with EDTA to treat cardiovascular disease with the hypothesis of moderating calcium to decrease atherosclerotic calcification of arteries. However, chelation with EDTA therapeutic effects in atherosclerotic cardiovascular disease is still unclear. Therefore, we propose to undertake a meta-analysis to assess the curative effects of EDTA chelation therapy in patients with atherosclerotic cardiovascular disease. In the current study, we set to perform a systematic literature search using the electronic databases of 4 most commonly used English databases (EMBASE, MEDLINE, Cochrane Library, and ClinicalTrials.gov trials register), as well as 3 most commonly employed Chinese databases (China Nation Knowledge Infrastructure, Wan Fang, and VIP), from the date of database inception until September 30, 2020 to identify relevant randomirosclerotic cardiovascular disease, which might be beneficial to these patients. The present study is a systematic review, hence the pooled results are founded upon the published evidence. Therefore, ethical approval is not necessary for the study. October 20, 2020.osf.io/tvmk8. (https//osf.io/tvmk8/). October 20, 2020.osf.io/tvmk8. (https//osf.io/tvmk8/). To explore the effect and mechanism of Shenfu Injec