When applying the proposed methods to these synthetic ground truth networks' clusters, as well as to other weighted networks with known community structure, these correctly identify the best performing algorithms, which suggests their adequacy for cases where the clustering structure is not known. We test our clustering validation methods on a varied collection of well known clustering algorithms applied to the synthetically generated networks and to several real world weighted networks. All our clustering validation methods are implemented in R, and will be released in the upcoming package clustAnalytics.Hate speech is one type of harmful online content which directly attacks or promotes hate towards a group or an individual member based on their actual or perceived aspects of identity, such as ethnicity, religion, and sexual orientation.  https://www.selleckchem.com/products/peg300.html  With online hate speech on the rise, its automatic detection as a natural language processing task is gaining increasing interest. However, it is only recently that it has been shown that existing models generalise poorly to unseen data. This survey paper attempts to summarise how generalisable existing hate speech detection models are and the reasons why hate speech models struggle to generalise, sums up existing attempts at addressing the main obstacles, and then proposes directions of future research to improve generalisation in hate speech detection.The worldwide coronavirus (COVID-19) pandemic made dramatic and rapid progress in the year 2020 and requires urgent global effort to accelerate the development of a vaccine to stop the daily infections and deaths. Several types of vaccine have been designed to teach the immune system how to fight off certain kinds of pathogens. mRNA vaccines are the most important candidate vaccines because of their capacity for rapid development, high potency, safe administration and potential for low-cost manufacture. mRNA vaccine acts by training the body to recognize and response to the proteins produced by disease-causing organisms such as viruses or bacteria. This type of vaccine is the fastest candidate to treat COVID-19 but it currently facing several limitations. In particular, it is a challenge to design stable mRNA molecules because of the inefficient in vivo delivery of mRNA, its tendency for spontaneous degradation and low protein expression levels. This work designed and implemented a sequence deep model based oSE) of 0.125 using LSTM model with augmentation and the codon encoding method. Codon encoding outperforms Base encoding in MCRMSE validation error using the LSTM model meanwhile Base encoding outperforms codon encoding due to less over-fitting and the difference between the training and validation loss error is 0.008.Baybayin is a pre-Hispanic Philippine writing system used in Luzon island. With the effort in reintroducing the script, in 2018, the Committee on Basic Education and Culture of the Philippine Congress approved House Bill 1022 or the "National Writing System Act," which declares the Baybayin script as the Philippines' national writing system. Since then, Baybayin OCR has become a field of research interest. Numerous works have proposed different techniques in recognizing Baybayin scripts. However, all those studies anchored on the classification and recognition at the character level. In this work, we propose an algorithm that provides the Latin transliteration of a Baybayin word in an image. The proposed system relies on a Baybayin character classifier generated using the Support Vector Machine (SVM). The method involves isolation of each Baybayin character, then classifying each character according to its equivalent syllable in Latin script, and finally concatenate each result to form the transliterated word. The system was tested using a novel dataset of Baybayin word images and achieved a competitive 97.9% recognition accuracy. Based on our review of the literature, this is the first work that recognizes Baybayin scripts at the word level. The proposed system can be used in automated transliterations of Baybayin texts transcribed in old books, tattoos, signage, graphic designs, and documents, among others.With the advent of the era of self media, the demand for video trading is becoming more and more obvious. Alliance blockchain has the characteristics of traceable transaction records, tamper proof transaction records, decentralized transactions and faster transaction speed than public chains. These features make it a trading platform. Trusted computing can solve the problem of non Byzantine attack in the aspect of hardware. This paper proposes a video transaction algorithm considering FISCO alliance chain and improved trusted computing. First, an improved trusted computing algorithm is used to prepare a trusted transaction environment. Second, the video summary information extraction algorithm is used to extract the summary information that can uniquely identify the video. Finally, based on the video transactions algorithm of FISCO alliance chain, the video summary information is traded on the chain. Experimental results show that the proposed algorithm is efficient and robust for video transactions. At the same time, the algorithm has low computational power requirements and algorithm complexity, which can provide technical support for provincial and county financial media centers and relevant media departments.Compi is an application framework to develop end-user, pipeline-based applications with a primary emphasis on (i) user interface generation, by automatically generating a command-line interface based on the pipeline specific parameter definitions; (ii) application packaging, with compi-dk, which is a version-control-friendly tool to package the pipeline application and its dependencies into a Docker image; and (iii) application distribution provided through a public repository of Compi pipelines, named Compi Hub, which allows users to discover, browse and reuse them easily. By addressing these three aspects, Compi goes beyond traditional workflow engines, having been specially designed for researchers who want to take advantage of common workflow engine features (such as automatic job scheduling or logging, among others) while keeping the simplicity and readability of shell scripts without the need to learn a new programming language. Here we discuss the design of various pipelines developed with Compi to describe its main functionalities, as well as to highlight the similarities and differences with similar tools that are available.