https://www.selleckchem.com/products/bal-0028.html pared with group 1, the two reviewers encountered significantly greater satisfaction with surgical outcomes among patients of group 2 (p < 0.01). In FACE-Q scoring, those undergoing lift-and-fill procedures reported the highest satisfaction levels. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 . This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 . Reduction mammoplasty in patients with gigantic breast hypertrophy runs a high risk of complication. Traditionally, inferior pedicle reductions or free nipple grafting techniques have been recommended for gigantic breasts on the basis of measurements and expected resection weights. The superiomedial pedicle (SMP) technique has been less commonly used, due to concerns of vascular inadequacy. This study examines the outcomes of SMP in large reductions and outlines suggested modifications for enhanced safety. This is a retrospective review of all patients who underwent SMP breast reduction in our institution between 2005 and 2016. Included are cases with resection weights greater than 800g. A total of 173 patients with 341 breasts were included. Mean sternal notch to nipple (SNN) distance was mean 35.0 ± 6.6cm (range 23-44.5) on the left and 34.9 ± 6.6cm (range 18-46) on the right. Mean resection weight was 1152.2 ± 368.6g (range 810-2926) on the left and 1159.4 ± 326.6g (range 800-2528) on the right. The e of Contents or the online Instructions to Authors www.springer.com/00266.Social media sites and platforms have grown in numbers with an enormous potential to reach and disseminate informatio