In this study, a heterogeneous activator was prepared via the Fe/Mn modification of sludge-derived biochar (Fe/MnBC) to achieve high-efficiency activation of persulfate (PS) for reactive blue 19 (RB19) degradation. The morphologies and chemical states of Fe/MnBC were examined by various characterizations. A comprehensive assessment was conducted to reveal the effects of biochar preparation conditions and system reaction conditions. According to the results of scavenger quenching experiments and electron paramagnetic resonance (EPR) testing, the mechanisms of Fe/MnBC combined PS system on RB19 degradation were proposed, including radical and non-radical mechanisms. The formation and involvement of sulfate radical (SO4·-), hydroxyl radical (OH·), and singlet oxygen (1O2) were proved in this system, and Fe(IV)/Mn(VII) was also speculated to participate in the non-radical degradation process. These findings give a new insight into the mechanisms of PS activated by metal-biochar composite. Besides, fixed-bed reactor (FBR) experiments indicated that the Fe/MnBC has considerable PS activation potential for dyes removal. The degradation process was further modeled by the central composite design (CCD-RSM) and artificial neural networks (ANN) methods. The statistical metrics and prediction indicated that the prediction results of ANN model were better than CCD-RSM model, and the ANN model could perfectly predict the reaction process of Fe/MnBC FBR for engineering applications.The factors causing air pollution in China has caused extensive concern, but there are still many problems in the grey incidence model of identifying air pollution factors.  https://www.selleckchem.com/products/ca-170.html  The results produced by the existing grey incidence models are not stable when the order of objects in a given panel data is changed. In order to improve the reliability and uniformity of the grey incidence model, a new grey incidence model, called the grey spatiotemporal incidence model, abbreviated as the GSTI model, is designed in this paper. In the proposed model, the spatiotemporal data which can represent the spatial relationship among different objects rather than the three-dimensional panel data are defined. In addition, the new model includes two procedures. Firstly, the trend coefficient is used to measure the positive and negative connections between two data sequences. Secondly, the measurement coefficient is utilized to calculate the size of grey incidence degree. Subsequently, five properties of the GSTI model are discussed. To demonstrate its practicability and compatibility, the novel model is utilized to identify south Jiangsu province's main factors causing air pollution according to monthly data for 2018. The abundant comparison shows the applicability and superiority of the model in the identification of air pollution factors and the construction of grey incidence model.
  To determine if the declining trend in U.S. youth cigarette smoking changed after e-cigarettes were introduced, and if youth e-cigarette users would have been likely to smoke cigarettes based on psychosocial and demographic predictors of smoking.
 
  An interrupted time series analysis was used for cross-sectional data from the 2004 to 2018 National Youth Tobacco Surveys (NYTS) to assess changes in cigarette and e-cigarette use over time. A multivariable logistic regression model used 2004-2009 NYTS data on psychosocial risk factors to predict individual-level cigarette smoking risk from 2011 to 2018. Model-predicted and actual cigarette smoking behavior were compared.
 
  The decline in current cigarette smoking slowed in 2014 (-0.75 [95% CI -0.81, -0.68] to -0.26 [95% CI -0.40, -0.12] percentage points per year). The decline in ever cigarette smoking accelerated after 2012 (-1.45 [95% CI -1.59, -1.31] to -1.71 [95% CI -1.75, -1.66]). Ever and current combined cigarette and/or e-cigarette use declined during 2011-2013 and increased during 2013-2014 with no significant change during 2014-2018 for either variable. The psychosocial model estimated that 69.0% of current cigarette smokers and 9.3% of current e-cigarette users (who did not smoke cigarettes) would smoke cigarettes in 2018.
 
  The introduction of e-cigarettes was followed by a slowing decline in current cigarette smoking, a stall in combined cigarette and e-cigarette use, and an accelerated decline in ever cigarette smoking. Traditional psychosocial risk factors for cigarette smoking suggest that e-cigarette users do not fit the traditional risk profile of cigarette smokers.
 The introduction of e-cigarettes was followed by a slowing decline in current cigarette smoking, a stall in combined cigarette and e-cigarette use, and an accelerated decline in ever cigarette smoking. Traditional psychosocial risk factors for cigarette smoking suggest that e-cigarette users do not fit the traditional risk profile of cigarette smokers.
  Appendectomies in children and adolescents are performed in Germany in pediatric surgical (PS) or general surgical hospitals (GS). The aim of this study is to evaluate whether the surgery in a PS or GS hospital has an influence on the postoperative course after appendectomy in children and adolescents.
 
  Nationwide routine data from children and adolescents aged 1-17y insured by the Local Health Insurance Fund who underwent appendectomy between 2014 and 2016 were analyzed (cohort study). Descriptive statistics were calculated both overall and in the two groups (PS and GS). Patients were additionally examined by age (1-5, 6-12, and 13-17y), treatment (laparoscopic, open surgical, and conversion), and appendicitis type (nonacute K36/K37/K38/R10, acute simple K35.30/K35.8, and acute complex K35.2/K35.31/K35.32). The influence of surgeon specialization on 90-d secondary surgery and 90-d general complications was assessed by multiple logistic regression.
 
  Altogether, 25,065 patients who underwent surgery in 83 PS and 906 GS hospitals were included. Logistic regression analysis revealed that PS was associated with a reduced risk of interventions in the 1-5- and 6-12-y age groups (odds ratio 0.44, 0.62). Acute complex appendicitis, comorbidities, and open surgery significantly increased the risk for reintervention. PS was associated with an increased risk for complications in the 13-17-y age group (odds ratio 1.66).
 
  PS and GS hospitals provided safe appendectomies in children and adolescents with low reintervention and complication rates. PS hospitals demonstrated advantages for patients in the 1-5- and 6-12-y age groups and GS hospitals for patients 13-17y.
 PS and GS hospitals provided safe appendectomies in children and adolescents with low reintervention and complication rates. PS hospitals demonstrated advantages for patients in the 1-5- and 6-12-y age groups and GS hospitals for patients 13-17 y.