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It has earned itself the status of one of the leading gaming platforms in the casino industry despite its relative infancy. The latest releases include Wolves, a 5-reel video slot with a healthful RTP and stunning graphics. Other notable titles include Wolf Gold and Chilli Heat. Pragmatic trials aim to mimic real-world situations and have the highest external validity. https://clamwind1.werite.net/why-nobody-cares-about-pragmatic-site are usually commissioned by policy makers and practitioners to guide their decision-making. They can also be used to assess the causality of an intervention and its effects. They should not, however, be used to replace explanation studies. The pragmatism concept is controversial, and there are questions about whether pragmatic trials should be used to replace explanatory trials or complement them. Schwartz and Lellouch1 suggested the distinction between explanation studies, which prove the validity of a physiological or clinical hypothesis, as well as pragmatic trials, which inform the practice and policy decision-making. They also suggested a framework for pragmatic trials, which they called PRECIS.2 This tool sought to define the elements of a pragmatic study, including the recruitment process, the design and delivery of the intervention, as well as follow-up. There is a growing trend in the number of pragmatic trials that are published. A recent Medline search using the words pragmatic and naturalistic, which was restricted to randomised controlled trials (RCTs), returned 34 articles. They are displayed in red on Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatic thinking. It is important to keep in mind that the majority of these trials were conducted in primary care settings.