https://www.selleckchem.com/peptide/pmx-205.html Virus, a sub-microscopic infectious agent that replicates only inside the living cells of a host causes viral infection. Currently the instant imperative is to control the combat against novel corona virus outbreak caused by COVID19 virus which started from China and spread all over the world. The ease of travel has emphasized COVID-19 virus prevention as a serious issue for the safety of human beings. Exponential rise in the number of corona patients is a matter of concern for governing bodies of various countries inspite of countless cooperative efforts put in by citizens, organizations and government. India is now among the top worst hit nation by the COVID-19 pandemic. The present article reviews stateof-art various medicinal approaches available that are presently used to control the spread of coronavirus pandemic. Hyperlipidemia is characterized by high level of cholesterol and triglycerides in blood. Various classes of drugs like statins, fibrates, niacin etc. are used for treatment of hyperlipidaemia. Niacin, which is one of the beneficial anti-hyperlipidemic agents, helps to lower LDL cholesterol by 20 to 40% and causes increase of HDL cholesterol by 20 to 35%. However cutaneous flushing, loss of glucose tolerance, liver toxicity are the reported side effects of niacin therapy responsible for decreased patient compliance. Very recently, the G protein coupled receptor (GPCR); GPR109A located on the adipocytes has been identified as the receptor for activation of niacin. In-vitro studies have demonstrated that GPR109A receptor having high affinity for niacin. The present review attempts to provide a systematic presentation of the various chemical classes of compounds that have been reported as novel niacin receptor agonists including pyrazole-3-carboxylic acids, urea derivatives, anthranilic acids, biaryl anthranilides, tetrahydro anthranilic acid, xanthines, barbituric acid, bicyclic pyrazole carboxylic acids,