https://www.selleckchem.com/products/sodium-ascorbate.html With growing incidence of early gastric cancer (EGC), endoscopic submucosal dissection (ESD) is widely performed as a standard treatment for mucosal cancer. Due to the increasing application of ESD, the number of non-curative resection after ESD is also growing, leading to escalating number of patients who require additional gastrectomy with lymph node dissection after non-curative ESD. However, effects of ESD prior to surgery on technical difficulties during operation for EGC remain unclear. Therefore, this study aimed to determine the effect of non-curative ESD on short-term surgical outcomes in patients who underwent additional surgical treatment using propensity score matching method. To evaluate the effect of ESD on short-term surgical outcomes in patients who underwent additional surgical treatment after a non-curative ESD procedure, patients were divided into two groups (1) those who underwent additional gastrectomy after non-curative resection of ESD [ESD+Surgery (ES) Group], and (2) those who underwent gastrectomy as the initial treatment [Surgery Only (SO) Group]. To minimize differences in baseline demographic features that could potentially be associated with short-term outcomes, propensity-scored matching analysis was performed. After propensity-scored matching (11 matching), 140 patients altogether were selected and analyzed in this study. Complications were experienced by 18 (25.7%) patients in the ES group and 13 (18.6%) patients in the SO group, showing no significant (p<0.416) difference between the two groups. Additional surgery after non-curative ESD can be safely applied, even within one month after ESD in terms of short-term complications. Additional surgery after non-curative ESD can be safely applied, even within one month after ESD in terms of short-term complications.Disclosure of personal substance use often places people who use drugs (PWUD) at risk, both personally and profession