https://www.selleckchem.com/products/curzerene.html We expect that this live cell membrane-spanning synthetic DNA nanopore will provide a tool for studying cellular communication, building synthetic cells, and achieving controlled transmembrane transport to cells.ConspectusCovalent organic frameworks (COFs) represent a novel type of crystalline porous polymers with potential applications in many areas. Considering their covalent connectivity in different dimensions, COFs are classified as two-dimensional (2D) layered structures or three-dimensional (3D) networks. In particular, 3D COFs have gained increasing attention recently because of their remarkably large surface areas (>5000 m2/g), hierarchical nanopores and numerous open sites. However, it has been proven to be a major challenge to construct 3D COFs, as the main driving force for their synthesis comes from the formation of covalent bonds. In addition, there are several stones on the roads blocking the development of 3D COFs. First, the successful topology design strategies of 3D COFs have been limited to [4 + 2] or [4 + 3] condensation reactions of the tetrahedral molecules with linear or triangular building blocks in the first decade, which led to only three available topologies (ctn, bor, and dia) and strongls field.Economical production of highly active and robust Pt catalysts on a large scale is vital to the broad commercialization of polymer electrolyte membrane fuel cells. Here, we report a low-cost, one-pot process for large-scale synthesis of single-crystal Pt multipods with abundant high-index facets, in an aqueous solution without any template or surfactant. A composite consisting of the Pt multipods (40 wt %) and carbon displays a specific activity of 0.242 mA/cm2 and a mass activity of 0.109 A/mg at 0.9 V (versus a reversible hydrogen electrode) for oxygen reduction reaction, corresponding to ∼124% and ∼100% enhancement compared with those of the state-of-the-art commercial Pt/C catalyst (0.108 mA