https://www.selleckchem.com/products/icg-001.html Chorea-acanthocytosis (ChAc) is an autosomal recessive, progressive neurological disorder due to mutation in VPS13A gene causing defects in sorting of protein making the cell membrane unstable, leading to star-shaped erythrocytes. This neurological disorder includes features such as elevated creatinine kinase, atrophy of basal ganglia, and oral manifestations such as frequent cheek and tongue biting. It is a rare neurological condition with an estimate of less then 1000 cases worldwide. A case of 47-year-old male patient with a history of seizures and neurological problems presenting with oral ulceration has been discussed. The diagnosis of ChAc was confirmed by molecular investigations showing VPS13A gene mutation. The physical appearance includes chorea and dystonia with impaired gait. We attempt to highlight the oral features of ChAc. The oral manifestations include frequent tongue and cheek biting occurring due to dystonia affecting the muscles of head and neck region.Overdentures are one of the most sought-after treatment options for patients with few remaining natural teeth. They are desired as they tend to preserve the natural teeth and its intact periodontium. This helps in reducing the residual ridge resorption and preserve proprioception. These characteristics offer better masticatory ability in patients rehabilitated with overdentures when compared to conventional complete dentures. Enhancements such as telescopic denture for better retention prove to be efficient clinically. Telescopic dentures enable frictional type of retention. This is a case report of a partially edentulous patient with decreased vertical dimension, successfully rehabilitated with telescopic denture in relation to the maxilla and fixed partial prosthesis in the mandibular region.Gingival enlargement can be multifactorial; it can be due to nutritional deficiency or can be because of several drugs. Poor oral hygiene may further worsen t