Infection with novel SARS-CoV-2 carries significant morbidity and mortality in patients with pulmonary compromise, such as lung cancer, autoimmune disease, and pneumonia. For early stages of mild to moderate disease, care is entirely supportive.Antiviral drugs such as remdesivir may be of some benefit but are reserved for severe cases given limited availability and potential toxicity. Repurposing of safer, established medications that may have antiviral activity is a possible approach for treatment of earlier-stage disease. Tetracycline and its derivatives (e.g. doxycycline and minocycline) are nontraditional antibiotics with a well-established safety profile, potential efficacy against viral pathogens such as dengue fever and chikungunya, and may regulate pathways important in initial infection, replication, and systemic response to SARS-CoV-2. We present a series of four high-risk, symptomatic, COVID-19+ patients, with known pulmonary disease, treated with doxycycline with subsequent rapid clinical improvement. No safety issues were noted with use of doxycycline.Doxycycline is an attractive candidate as a repurposed drug in the treatment of COVID-19 infection, with an established safety profile, strong preclinical rationale, and compelling initial clinical experience described here.The reviews of this paper are available via the supplemental material section.Joint Medical Master University of Lucerne and University of Zurich Abstract. The medical education in Switzerland is changing. On the one hand, the new, competence-based catalogue of learning objectives PROFILES has to be implemented. On the other hand, new training locations and cooperations have been created within the context of the special program 'Increasing the number of degrees in human medicine'.  https://www.selleckchem.com/products/iruplinalkib.html  One of these cooperations is the Joint Medical Master of the Universities of Lucerne and Zurich. Since 2017, students have had the opportunity to complete their Bachelor's degree at the University of Zurich in the 'Lucerne Track'. In the subsequent joint Master's program (start fall semester 2020), the approximately 40 students are primarily enrolled at the University of Lucerne, which together with its partner institutions in the health care region of Central Switzerland offers about two thirds of the courses. At the University of Lucerne, which has a strong emphasis on social and human sciences, the Departas in the evaluation of the courses, and the lecturers are prepared as well as possible for their teaching duties by continuing medical education events. In the medium term, the University of Lucerne would also like to focus more on the continuum of pre- and postgraduate training, and to network nationally and internationally in the medical education landscape.Studying Human Medicine at the University of Geneva An Up-to-Date, Integrated Curriculum Abstract. The curriculum of human medicine at the Faculty of Medicine of the University of Geneva has been thoroughly renovated in 1995. It offers an integrated program allowing for a constant adaptation of the content to the explosion of biomedical knowledge and the changes in society. It uses active, student-centred learning methods. In line with the Bologna process since 2006, it has been accredited several times, most recently in 2019. It evolved to strengthen the importance of primary care and to introduce interprofessional training, in particular through its simulation centre. Through early and continuous clinical immersion, students acquire their practical skills in an integrated manner. These conditions are conducive to the introduction of new concepts, such as the Entrustable Professional Activities (EPAs) conveyed by the recent national competence framework PROFILES.Studying Human Medicine at the University of Zurich Abstract. We compile the most important published information on studying human medicine at the Medical Faculty of the University of Zurich (as of 8.6.2020), with a brief overview of the 'Education Network' (www.medunet.ch) of the six participating locations with the Universities of Zurich, Basel, St. Gallen, Lucerne, the Università della Svizzera italiana and the ETH Zurich. Within the educational network, the Universities of Lucerne and St. Gallen offer the so-called 'Lucerne Track' and 'St. Gallen Track' for 40 medical students each as a joint Master's program with the University of Zurich. The two partners present their curriculum in separate articles. Finally, information on the current curriculum revision is provided under the label ZH Med4, which stands for the main focus areas of digitization, research, networking and primary care.CME Sonography 93 Ultrasound of the Enthesis - Not Every "Enthesitis" Signals a Spondyloarthritis Abstract. In this CME we will focus on the ultrasound anatomy of the enthesis. In addition, we describe the terms enthesopathy and enthesitis and discuss related differential diagnostic considerations. It is important to know all the diseases that can manifest themselves at the enthesis, so that diagnoses can be made, and patients classified correctly. At this point it is worth mentioning that the findings of enthesitis do not necessarily need to be associated with spondylarthritis.Studying Medicine at the Università della Svizzera Italiana Abstract. The Faculty of Biomedical Sciences (Faculty) of the Università della Svizzera italiana (USI) was founded in 2014 with the aim of contributing to the solution of a problem that affects the whole of Switzerland the lack of doctors trained in Switzerland. In order to achieve this goal, the Faculty, in collaboration with the University of Basel, has been offering a limited number of Bachelor's study places since 2017, and in autumn 2020 the new Master's programme in Human Medicine will start in Ticino. On the academic side, the Faculty cooperates closely with the Swiss Federal Institute of Technology Zurich (ETHZ), the University of Basel (UNIBAS) and the University of Zurich (UZH), and for the clinical training there are collaborations with various clinical institutions in Ticino. By combining clinical practice, scientific training and communication skills, the Master's degree addresses the challenges of today's medical profession.