https://www.selleckchem.com/products/m344.html The relationship of differentially-expressed genes of interest to biologic pathways was explored using the Database for Annotation, Visualization and Integrated Discovery (DAVID). This exploratory investigation indicates that cannabis oil extract may affect expression of specific airway epithelial cell genes that could modulate pro-inflammatory or Th1 processes in COPD. These results provide a basis for further investigations and have prompted in vivo studies of the effects of cannabis oil extract on pulmonary function. NONE (all in vitro experiments). NONE (all in vitro experiments). Ohio's medical cannabis program is one of three states that require physicians to become certified to recommend medical cannabis to their patients. The current study examines the attitudes of Ohio physicians toward medical cannabis and Ohio's program to ascertain how likely physicians are to participate in Ohio's program. Physicians were invited to complete an internet survey that asked them about their concerns regarding medical marijuana, Ohio's program, their likelihood of recommending medical cannabis, and becoming certified within the state. Ordinal and logistic regressions were used to understand the physicians' likelihood of recommending cannabis, of becoming certified to recommend cannabis, and their attitude toward Ohio's program. In total, 11,665 physicians licensed to practice in Ohio were contacted by email, and 344 responses were received for a response rate of 2.9%. Only 42 physicians reported being certified or had plans to become certified to recommend marijuana, and 62% were unlikely toing cannabis in healthcare, along with requiring "certified recommenders" to have training could result in a fractured healthcare system. The results show that many physicians have concerns about medical cannabis and Ohio's program, and many physicians may not participate in the program. This could be a problem for patients who would like to