https://www.selleckchem.com/products/gsk3326595-epz015938.html This article studies the shift from a Ministry of Hygiene in Colombia to a Ministry of Public Health, from 1946 to 1953. This was not only a new name for the ministry, but a transitional process from government policies based on European public hygiene towards institutionalizing the North American model of public health. The process involved negotiations between local government representatives and the Currie Mission, which was sent to Colombia by the Inter-American Bank for Reconstruction and Development and the Inter-American Cooperative Health Service. These negotiations took place via asymmetrical relationships of interdependence, within the framework of the "invisible government" implemented by the United States in Latin America during the Cold War.The first half of the twentieth century was marked globally by a nationalist shift, which also affected science. The initiatives to block some "national science" (especially from Germany) and the discussions that flooded Western public space are hallmarks of the radical transformations that knowledge and power underwent at the time. Based on historical literature from the time, the article explores the growing polarization of scientific discourse in the first half of the twentieth century. Special attention is given to the interwar period, the (re)founding (after 1918) of international scientific organisms based in Europe (like the International Research Council), and the prohibition of the journal Nature in Nazi Germany in 1937.This work analyzes the representations of the toxic risks of hexachlorocyclohexane, an active ingredient of many pesticides commonly used in Spanish fields during Franco's regime. Emphasis is placed on the practices that visibilized and invisibilized these risks, seeking to establish the actors that promoted them and the mechanisms they used. From the perspective of agnotology, I analyze the generation of ignorance and uncertainty