https://www.selleckchem.com/products/iwp-2.html 05). The relationship of IOP and testosterone was significantly associated with only normal groups according to the degree of obesity (p<0.05). The IOP in patients with testosterone above 3.0 ng/mL was significantly higher than testosterone below 3.0 ng/mL (p<0.05). The correlation of IOP-testosterone has a significantly positive relationship, in case of healthy men with normal weight by OI or BMI. The correlation of IOP-testosterone has a significantly positive relationship, in case of healthy men with normal weight by OI or BMI.It is widely accepted that oxidative stress plays an important role in the pathophysiology of male infertility and that antioxidants could have a significant role in the treatment of male infertility. The main objectives of this study are 1) to systematically review the current evidence for the utility of antioxidants in the treatment of male infertility; and 2) propose evidence-based clinical guidelines for the use of antioxidants in the treatment of male infertility. A systematic review of the available clinical evidence was performed, with articles published on Scopus being manually screened. Data extracted included the type of antioxidant used, the clinical conditions under investigation, the evaluation of semen parameters and reproductive outcomes. The adherence to the Cambridge Quality Checklist, Cochrane Risk of Bias for randomized controlled trials (RCTs), CONSORT guidelines and JADAD score were analyzed for each included study. Further, we provided a Strength Weakness Opportunity Threat (SWOT) analysn quality.Paternal health and behavioral lifestyles affect reproductive and neonatal outcomes and yet the magnitude of these effects remain underestimated. Even though these impacts have been formally recognized as a central aspect of reproductive health, health care services in Europe often neglect the involvement of fathers in their reproductive programs. Following the PRISMA (Preferred