Neural mobilization (NM) techniques have been shown to improve the neural tissue's viscoelastic properties that may lead to recover of the function of the nerve after lumbar spine surgery. This study aimed to determine the effects of NM in addition to standard rehabilitation on lumbar and sciatic pain intensity, disability level, and quality of life in patients after receiving a microdiscectomy of the intervertebral lumbar disc (IVD).
 
  Twenty-four participants (age 41.3±8.3 years old) within 3-4 weeks of a microdiscectomy of an IVD were randomly allocated to control (CTRL; n=12) or NM group (n=12). The CTRL group received ten standard rehabilitation sessions. The NM group received the same rehabilitation sessions with the addition of NM techniques. The intensity of lumbar and sciatic pain (visual analogue scale), disability level (Oswestry disability index), and health-related quality of life (SF-36 questionnaire) were measured before and after the intervention.
 
  Within-group analysis revealed a significant reduction in lumbar (p<0.05) and sciatic pain intensity (p<0.001), disability level (p<0.001), and improvement in the physical function and problems, vitality, emotional well-being, and pain SF-36 items (p<0.05) in both groups. There were no statistical differences between groups in all outcomes.
 
  A standard rehabilitation protocol alone or in combination with NM techniques are equally effective in reducing pain and disability level, as well as improving quality of life in patients after a microdiscectomy due to intervertebral lumbar disc lesion.
 A standard rehabilitation protocol alone or in combination with NM techniques are equally effective in reducing pain and disability level, as well as improving quality of life in patients after a microdiscectomy due to intervertebral lumbar disc lesion.
  To analyze the effects of whole body vibration on electromyographic activity of the core muscles.
 
  This is an observational cross-sectional study composed of 30 males who practice physical activity. The amplitude of the electromyographic activation (Root Mean Square - RMS) of the rectus abdominis, external oblique, longissimus thoracis, multifidus muscles were evaluated during supine bridge, side plank and frontal plank exercises, performed with and without vibration (frequency 50 Hz and amplitude 4 mm). A significance level of 5% was assigned for all analyzes.
 
  Whole body vibration did not alter the amplitude of electromyographic activity for any of the evaluated muscle groups, showing no difference between the conditions with and without vibration during the performance of the proposed exercises.
 
  Under the conditions analyzed in this study, the vibrating platform does not change the activation amplitude of core muscles, suggesting that the use of whole body vibration is not necessary as an additional method to increase muscle activity during stabilization exercises in healthy men.
 Under the conditions analyzed in this study, the vibrating platform does not change the activation amplitude of core muscles, suggesting that the use of whole body vibration is not necessary as an additional method to increase muscle activity during stabilization exercises in healthy men.The aim of this work was to select and identify the best markers of aromatic hydrocarbon mineral oil (MOAH) in food packaging. For this purpose, a series of mineral oils was initially analysed.  https://www.selleckchem.com/  Polycyclic Aromatic Hydrocarbons (PAHs) and the alkylated isomers of Methylnaphthalene (MNS), Diisopropylnaphtalene (DIPNs), Dibenzothiophenes (DBTS), Methyldibenzothiophene (MDBTs), Dimethyldibenzothiophenes (DMDBTs) and Benzonaphthiophenes (BNTS) were then explored. Their presence was confirmed by direct analysis of several mineral oils by Atmospheric Solids Analysis Probe Quadrupole-Time of Flight Mass Spectrometry (ASAP-QTOF-MS). Atmospheric Pressure Gas Chromatography Quadrupole-Time of Flight Mass Spectrometry (APGC-QTOF-MS) was used to confirm the markers in different samples of oils, recycled PET (rPET), recycled cardboard and packaging of couscous and semolina to confirm the contamination. 27 markers were found in the mineral oil samples, 22 of them in rPET, 8 in recycled board and no MOAH were found in packaging of couscous and semolina.A lysosome-targeting ratiometric fluorescent nanoprobe based on cell-penetrating peptides (CPPs) and quantum dots (QDs) has been developed for monitoring pH fluctuation in living cells. The as-prepared nanoprobe is constructed by Rhodamine B labeled R9RGD CPPs as H+ response unit and the red fluorescent QDs as reference unit to achieve ratiometric pH measurement. With the help of RhB-R9RGD CPPs, the nanoprobe efficiently stains lysosomes and enables discernment of lysosomal pH fluctuation in cells treated with different pH buffers and drug stimulation. The method of using dye labeled CPPs to realize functionalization of nanoparticle in one-step reported herein is expected to obtain wider applications in the detection of subcellular active substances by combining different small molecular probes and functional peptides.Since December 2019, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has caused millions of deaths and seriously threatened the safety of human life; indeed, this situation is worsening and many people are infected with the new coronavirus every day. Therefore, it is very important to understand patients' degree of infection and infection history through antibody testing. Such information is useful also for the government and hospitals to formulate reasonable prevention policies and treatment plans. In this paper, we develop a lateral flow immunoassay (LFIA) method based on superparamagnetic nanoparticles (SMNPs) and a giant magnetoresistance (GMR) sensing system for the simultaneously quantitative detection of anti-SARS-CoV-2 immunoglobulin M (IgM) and G (IgG). A simple and time-effective co-precipitation method was utilized to prepare the SMNPs, which have good dispersibility and magnetic property, with an average diameter of 68 nm. The Internet of Medical Things-supported GMR could transmit medical data to a smartphone through the Bluetooth protocol, making patient information available for medical staff.