https://www.selleckchem.com/products/a2ti-2.html Furthermore, the indirect soft-agar assay was used as a tool to unravel the global functional impact of the found secretome changes. Our results indicate that the GBN-induced altered secretome can modify the natural anchorage-independent growth capacity of HeLa cells, used as a model. As a conclusion, this study describes an innovative approach to study the potential harmful effects of GBN, providing relevant data to be considered in the biomedical context when GBN are planned to be used in patients.Competitive adsorption of arsenate (AsO43-) and phosphate (PO43-) on α-FeOOH, LaOOH, and nano-TiO2 was studied using batch adsorption experiments and in-situ flow cell ATR-FTIR coupled with two-dimensional correlation spectroscopy (2D-COS) for the first time. With a higher temporal resolution, our results found a highly dynamic adsorption sequence for AsO43- and PO43-. When AsO43- and PO43- were simultaneously exposed to the adsorbents at the same concentrations, AsO43- was preferentially adsorbed by α-FeOOH and TiO2, but PO43- adsorption was dominant on LaOOH. The results implied that the PO43- adsorbed on LaOOH had to be remobilized to allow for AsO43- adsorption, but that PO43- adsorption on α-FeOOH and TiO2 was hindered by faster AsO43- adsorption. Crystal orbital Hamilton population (COHP) analysis revealed that AsO43- complexes bonded more strongly on α-FeOOH and TiO2, whereas PO43- complexes were more stable on LaOOH. Different adsorption sequences and the stability of the complexes were attributed to the diverse geometric configurations of AsO43- and PO43- on metal oxides surfaces with specific bonding chemistry. The presence of Ca2+ did not affect AsO43- and PO43- adsorption sequence on α-FeOOH or LaOOH, but it reversed the adsorption sequence on TiO2 due to the formation of ternary surface complexes on TiO2 surfaces.In this work, fibrous silica-titania (FST) was successfully prepared by the microemulsion method p