The deformation behavior and fracture mechanism of cast duplex stainless steel tubular specimens under different tensile stages were investigated through experimental and numerical evaluation. The results showed that the axial stress was redistributed due to the necking of the tubular specimen, the axial stress near the internal wall was larger than those near the external wall, and its maximum axial stress was distributed between the internal wall and the center of the wall thickness. Microcracks and voids were initiated under the maximum shear stress along the δ/γ phase interface and propagated to the ferrite interior. The voids were connected and merged into the main crack through the propagation of the microcracks. Moreover, the main crack first propagated to the internal wall and then rapidly propagated to the external wall. The fracture morphology can be divided into three types shear lip zones that can be found on both the internal and external walls, and shear lip zones that can be found on either only the internal wall or the external wall.Natural products have a long history of use for skincare and the improvement of the appearance and function of aged and/or damaged skin [...].The transcriptome profile and differential gene expression in telogen and late anagen microdissected hair follicles and the interfollicular epidermis of healthy dogs was investigated by using RNAseq. The genes with the highest expression levels in each group were identified and genes known from studies in other species to be associated with structure and function of hair follicles and epidermis were evaluated. Transcriptome profiling revealed that late anagen follicles expressed mainly keratins and telogen follicles expressed GSN and KRT15. The interfollicular epidermis expressed predominately genes encoding for proteins associated with differentiation. All sample groups express genes encoding for proteins involved in cellular growth and signal transduction. The expression pattern of skin-associated genes in dogs is similar to humans. Differences in expression compared to mice and humans include BMP2 expression mainly in telogen and high KRT17 expression in the interfollicular epidermis of dogs. Our data provide the basis for the investigation of the structure and function of canine skin or skin disease and support the use of dogs as a model for human cutaneous disease by assigning gene expression to specific tissue states.In this article, we report the results of experimental studies on the impact of ball burnishing parameters on the roughness, microstructure and microhardness of the surface layer of laser-cut C45 steel parts. We also analysed the distribution of residual stresses generated in the surface layer of these parts. Laser-cut parts often require finishing to improve the quality of their surface. The tests performed in this study were aimed at assessing whether ball burnishing could be used as a finishing operation for parts of this type. Ball burnishing tests were performed on an FV-580a vertical machining centre using a mechanically controlled burnishing tool. The following parameters were varied during the ball burnishing tests burnishing force Fn, path interval fw and the diameter of the burnishing ball dn. Ball burnishing of laser-cut C45 steel parts reduced the surface roughness parameters Sa and Sz by up to 60% in relation to the values obtained after laser cutting. Finish machining also led to the reorganization of the geometric structure of the surface, resulting in an increase in the absolute value of skewness Ssk. This was accompanied by an increment in microhardness (maximum microhardness increment was ΔHV = 95 HV0.05, and the thickness of the hardened layer was gh = 40 µm) and formation of compressive residual stresses in the surface layer.Low vaccination coverage of livestock is one of the major challenges to control anthrax in Bangladesh. This study was conducted to assess an alternate approach to maximize vaccination coverage. The method included traditional vaccination campaigns, livestock census, interviews, focus group discussions of cattle farmers, vaccination and livestock personnel, and validation workshops. It was observed that a mass vaccination program covered only 44% of the cattle population. It was found that 54.1% of the respondents did not bring their cattle to mass vaccination programs due to the difficulties of handling cattle and that there was no male member in the household. Only 12.5% of respondents acknowledged that they were not aware of the vaccine, and 3% of the respondents claimed that they ignored vaccination due to cost. All of the respondents from livestock personnel agreed that manpower was not enough to cover the total area.  https://www.selleckchem.com/products/ZM-447439.html  Further, 20% of vaccinators mentioned that they did not get enough vaccines. For an effective vaccination program, 58.33% of respondents recommended door-to-door service, and 54.16% of respondents suggested to arrange regular vaccination campaigns in six-month intervals. Thus, regular campaigns with door-to-door vaccination services are suggested to control anthrax outbreaks in Bangladesh.Walking on different terrains leads to different biomechanics, which motivates the development of exoskeletons for assisting on walking according to the type of a terrain. The design of a lightweight soft exoskeleton that simultaneously assists multiple joints in the lower limb is presented in this paper. It is used to assist both hip and knee joints in a single system, the assistance force is directly applied to the hip joint flexion and the knee joint extension, while indirectly to the hip extension also. Based on the biological torque of human walking at three different slopes, a novel strategy is developed to improve the performance of assistance. A parameter optimal iterative learning control (POILC) method is introduced to reduce the error generated due to the difference between the wearing position and the biological features of the different wearers. In order to obtain the metabolic rate, three subjects walked on a treadmill, for 10 min on each terrain, at a speed of 4 km/h under both conditions of wearing and not wearing the soft exoskeleton.