https://www.selleckchem.com/products/Tranilast.html Hypodermic needles and syringes are currently the main route of the transdermal administration. Many complaints associated with needle-stick injuries, needle phobia, and needle abuse have motivated the development of alternative drug delivery strategies. Pneumatic needle-free injections stand out from various alternative strategies because of the convenience in adjusting the driving pressure and the injection volume. This study proposed a novel control method of the pneumatic needle-free injection for delivering larger volume drugs to the target sites at desired rates and time by controlling the driving pressure. The dynamic characteristics of this injection mode were evaluated in the impact experiments and the results confirmed the reliability of this controllable system in controlling the outlet pressure and jet velocity. The injection performances of it were compared with that of other injection modes through in vivo and in vitro experiments. This controllable system was able to control the injection depth and it was more conducive to the lateral diffusion of the liquid jets in gelatin. Moreover, it could not only enlarge the diffusion of diclofenac solution in rats, but also accelerate the metabolism of diclofenac solution in rats. All experimental results confirmed the reliability of this controllable injection system. Cryopreservation was first studied in early twentieth century, and the cryopreservation of cell and tissue samples has become an inseparable process in biology research labs, helping scientists to store living materials and to accumulate specimens. Recently, a new and simplified cryopreservation product, BioFlash Drive™ SP developed by a US firm Fibulas, came to the attention of many researchers. It integrates the sample container with control-released cryoprotectant, and the container itself can achieve slow-freezing in deep freezers. This means no reagents mixing or extra steps for slow-freezi