https://www.selleckchem.com/products/o-pentagalloylglucose.html The streptavidin-biotin affinity was utilised to demonstrate the potential of the birefringence assay platform, using free biotin as the model analyte, biotinylated lipase and streptavidin-coated magnetic beads in the competitive format. A semi-quantitative assay with a detection limit of 5 μg mL-1 to free biotin as the model analyte was achieved in the visual birefringence mode. This study demonstrated a proof-of-concept lyotropic assay platform with birefringence as the visual signal output that could be deployed as an electronics- and colour-free diagnostic device for a wide range of applications, for example to indicate the presence of toxins in water.The development of new multi-functional dressing materials that effectively combine excellent antibacterial and wound healing promotion properties are highly desirable in modern biomedical research and clinical practice. In this study, a new near-infrared photo-responsive dressing material (HG1-CW) was fabricated based on a dodecyl-modified and Schiff base-linked chitosan hydrogel, a photothermal agent (WS2 nanosheets), and an antimicrobial drug (ciprofloxacin). This nanocomposite dressing possesses the advantages of being injectable, self-adapting, rapidly molding, and has good tissue adherence and excellent biocompatibility. The positive charge, macropore, and alkyl chain of the hydrogel helped to capture and restrict the bacteria. Under the irradiation of near-infrared light, the WS2 nanosheets produced a large amount of heat and simultaneously, the antibiotic was triggered to release in an on-demand fashion at the wound site, leading to the bacterial death. This synergistic therapy combining the photothermal effect and the spatially and temporally controlled drug release effectively avoided the shortcomings of each of the two individual treatment modes, and the outstanding sterilizing effect was verified by both the in vitro antibacterial tests and