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Tramadol is a prescription medication used to manage moderate to moderately severe pain. It is classified as an opioid analgesic, but it has a unique mechanism of action. Tramadol works by binding to opioid receptors in the brain and also inhibits the reuptake of neurotransmitters like serotonin and norepinephrine, which contribute to its pain-relieving effects.  It also inhibits the reuptake of norepinephrine and serotonin, neurotransmitters involved in pain modulation.