https://www.selleckchem.com/products/ngi-1ml414.html 005 for all parameters). The most powerful predictor for MACE among our study population is 4D-GAS, with the best cutoff value of 4D-GAS >-17 ( = 0.008; odds ratio = 20.668; confidence interval = 2.227-191.827). The novel 4D-GAS echocardiography predicts adverse clinical events in STEMI patients managed by successful primary PCI. The novel 4D-GAS echocardiography predicts adverse clinical events in STEMI patients managed by successful primary PCI. Obesity-related pulmonary arterial hypertension (PAH) is associated with hypoxia and metabolic abnormalities. Although right heart catheterization is the gold standard method for the diagnosis of PAH, Doppler echocardiography is more common. On the other hand, there is no definite echocardiographic parameter for PAH diagnosis. Novel echocardiographic parameter, pulmonary pulse transit time (pPTT), is assumed to be a surrogate marker for the assessment of PAH. The aim was to evaluate whether pPTT might be valuable for evaluating pulmonary vascular hemodynamics in obese patients. A cross-sectional observational study. A total of 130 consecutive obese patients and 50 controls were included. Obese patients were divided into three groups according to body mass index (BMI) 25 < BMI <30 kg/m formed Group 1, 30 < BMI <35 kg/m formed Group 2, and 35 <BMI kg/m formed Group 3. All patients underwent a standard echocardiography including pPTT measurement. pPTT was defined as the interval betwetermination of the pulmonary hemodynamics in obese patients. pPTT might be a useful parameter in terms of predicting pulmonary hemodynamics and vascular alterations in obese patients. Further studies are warranted to evaluate the association between obesity and PAH. The results of this study suggest that obesity leads to an increase in PAH, and pPTT allows noninvasive determination of the pulmonary hemodynamics in obese patients. pPTT might be a useful parameter in terms of predicting pulmonary