https://www.selleckchem.com/products/BIBF1120.html The results obtained suggest a role of endocannabinoid system in the regulation of food intake in fish at central level but further studies are required to fully elucidate the mechanisms involved. The results obtained suggest a role of endocannabinoid system in the regulation of food intake in fish at central level but further studies are required to fully elucidate the mechanisms involved. The efficacy of omega-3 fatty acids in the treatment of sepsis is controversial. We conducted an updated meta-analysis to clarify the efficacy of omega-3 fatty acids in patients with sepsis. PubMed, EMBASE, and the Cochrane Library were searched for randomized clinical trials (RCTs) on omega-3 fatty acid supplementation in adults with sepsis. Twenty eligible RCTs involving 1514 patients were included in the meta-analysis. Omega-3 fatty acid supplementation was linked to reductions of mortality (  = 0, relative risk [RR] = 0.82, 95% confidence interval [CI] = 0.69-0.97), the duration of mechanical ventilation (DMV;  = 74%, weighted mean difference [WMD] = -2.20, 95% CI = -4.00 to -0.40), and intensive care unit (ICU) length of stay (LOS;  = 91%, WMD = -3.86, 95% CI = -5.72 to -2.01). Subgroup analysis illustrated that mortality was significantly reduced in patients with sepsis and gastrointestinal dysfunction (RR = 0.5, 95% CI = 0.29-0.86,  = 0). Omega-3 fatty acid supplementation might be associated with reduced mortality in patients with sepsis, especially those with gastrointestinal dysfunction. Furthermore, omega-3 fatty acid administration could shorten DMV and ICU LOS. Omega-3 fatty acid supplementation might be associated with reduced mortality in patients with sepsis, especially those with gastrointestinal dysfunction. Furthermore, omega-3 fatty acid administration could shorten DMV and ICU LOS.INTRODUCTION Preeclampsia (PE), but mainly preterm PE, is associated with deep placentation disorders. We aimed to compare placent