e. thermosonication treated hydrolysate of white kidney bean. Changes in secondary and tertiary structures were also analyzed under different processing conditions with maximum change due to thermosonication. Results indicated that mung bean hydrolysate had a great potential for inhibition of cholesterol synthesis and its solubility in the micelle, antioxidant activity and also convinced for its application in food and nutraceutical industries.  https://www.selleckchem.com/products/jtc-801.html  PURPOSE Phenytoin (PHT) is a common causative drug for severe cutaneous adverse drug reactions (SCARs) in children. SCARs, including drug reaction with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are associated with a variation in HLA genotypes. Blood screening for specific HLA allele before PHT prescription would help in the reduction of the incidence of PHT induced SCARs. This study was to investigate the association between variations of HLA genotypes and PHT induced SCARs in Thai children. METHODS Cases were Thai children aged between 0-18 years diagnosed with SCARs from PHT. Control groups were Thai children of corresponding age who had taken PHT for a least 12 weeks without any hypersensitivity reaction and healthy population controls. Blood samples from both groups were collected for HLA genotyping using a reverse-sequence specific oligonucleotide (SSO) probes method. Carrier rates of HLA alleles were compared between 22 cases (17 DREHT induced DRESS and HLA-B*3802 and PHT induced SJS-TEN has been demonstrated in Thai children. HKUST-1, a Cu-based metalorganic framework (MOF), was synthesized solvothermally, functionalized with polyethyleneimine (PEI), and hybridized with graphene oxide (GO) and functionalized GO for H2S removal. MOF synthesis approach, molecular weight of amines, and the content of GO in the hybrid adsorbents were systematically varied. The adsorbent materials were characterized by XRD, FTIR, SEM, elemental analysis, liquid N2 adsorption-desorption, water vapor and oxygen sorption, and subsequently tested for H2S adsorption in a breakthrough column. The MOF in the composite adsorbents consisting of in-situ grown HKUST-1 on GO that was pre-functionalized with low molecular weight PEI exhibited the highest H2S adsorption uptake at ambient conditions (0.9 mmol S g-1 MOF) in comparison to 0.5 mmol S g-1 MOF for the parent HKUST-1, thus showing an 80 % increase in uptake, while this material also exhibited significantly enhanced sorption kinetics. H2S adsorption at higher temperature (150 °C) was also performed, and at this temperature a HKUST/GO hybrid adsorbent resulted in the highest MOF capacity, i.e. 2.1 mmol S g-1 MOF, which is 27 % higher than that of the parent MOF at the same conditions. Formation of hybrid adsorbents with GO coupled to tunable functionalization of both GO support and the MOF crystallites can contribute in optimizing H2S capture performance of MOFs. In this study, the photo-transformations of bulk C3N4 (CN) and oxidized C3N4 (OCN) under UV-irradiation were examined. Through NO3- release measurements, we found that the photo-transformation rate of OCN is higher than that of CN. Various characterization results revealed the structural and chemical properties changes of CN and OCN after photo-transformation. We proposed that under reactive oxygen species attack, CN and OCN were gradually broken into smaller fragments and finally mineralized into NO3-, CO2, and H2O through the circular reactions of deamination-hydroxylation-decarboxylation. Through the zeta potential measurements and sedimentation experiments, the influence of photo-transformation on the water stabilities of CN and OCN were assessed. The stability of CN in water increased while the water stability of OCN decreased after photo-transformation, implying that the changes to C3N4-based materials caused by photo-transformation may significantly impact their environmental behaviors. Moreover, the photocatalytic activities of the photo-transformed OCN and CN substantially decreased, indicating that the structural changes might be the main reason for their photocatalytic activity loss. These findings highlight the non-negligible influence of photo-transformation on the fate of C3N4 in aquatic environments, as well as on the photochemical stability during its use. Molybdenum disulfide sheets loaded with copper nanoparticles (MoS2-CuNPs) was prepared and its antibacterial activity against phytopathogen Xanthomonas oryzae pv. oryzae (Xoo) was investigated in vitro and in vivo for the first time. In a 2 h co-incubation, MoS2-CuNPs exhibited 19.2 times higher antibacterial activity against Xoo cells than a commercial copper bactericide (Kocide 3000). In the detached leaf experiment, the disease severity decreased from 86.25 % to 7.5 % in the MoS2-CuNPs treated rice leaves. The results further demonstrated that foliar application of MoS2-CuNPs could form a protective film and increase the density of trichome on the surface of rice leaves, finally prevent the infection of Xoo cells. This was probably due to the synergistic effect of MoS2-CuNPs. Additionally, foliar application of MoS2-CuNPs (4-32 μg/mL) increased obviously the content of Mo and chlorophyll (up 30.85 %), and then improved the growth of rice seedlings. Furthermore, the obtained MoS2-CuNPs could activate the activities of the antioxidant enzymes in rice, indicating higher resistance of rice under abiotic/biotic stresses. The multifunctional MoS2-CuNPs with superior antibacterial activity provided a promising alternative to the traditional antibacterial agents and had great potential in plant protection. The effects of different proportions of cattle manure (CM) and biogas residue (BR) on the degradation of lignocellulose and humification during composting were investigated. The results showed that increasing the CM content prolonged the thermophilic period duration, thus promoting organic matter degradation and enhancing the humification degree during composting. Compared with the initial compost, the cellulose content decreased 3.90%-22.81%. The addition of CM increased humic acid content by 17.21%-26.02% compared with the control. The excitation-emission matrix (EEM) fluorescence spectroscopy analysis indicated that a higher CM content was conducive to the formation of protein-like substances, but a disadvantage for humic substances. The cell viability decreased as CM content increased. The redundancy analysis (RDA) demonstrated that proportions of CM and BR were positively correlated with cellulose content and negatively correlated with cell viability and the content of lignin. The results suggest that adding 6.