https://www.selleckchem.com/products/jtc-801.html 4 mSv (thorax) per fraction for a risk estimate of 0.004% (brain), 0.01% (H&N), 0.1% (pelvis), and 0.2% (thorax). Calculated ESD were compatible with existing data. CONCLUSIONS Dose calculation models for CyberKnife IGRT kV beams were implemented in a clinical treatment planning system and validated in water and heterogeneous phantoms. We determined the effective dose and the related risk estimate resulting from CyberKnife IGRT protocols for brain, head and neck, thorax, and pelvis cases. The effective doses calculated for CyberKnife IGRT protocols were similar to those obtained for cone beam CT protocols on conventional C-arm linear accelerators, except for extreme irradiation conditions for thorax cases (140 kV X-ray tube tension). © 2020 American Association of Physicists in Medicine.OBJECTIVES The aim of this study was to detect visual field defects (VFD) after occipital infarction, investigate the rate of recovery and the impact of VFD upon vision related quality of life (QoL). MATERIALS & METHODS Multicenter, prospective study including patients with MRI verified acute occipital infarction (NOR-OCCIP project). Ophthalmological examination including perimetry was performed within two weeks and after six months. Vision related QoL was assessed by the National Eye Institute Visual Function Questionnaire 25 (VFQ-25) at one and six months post stroke. RESULTS We included 76 patients, reliable perimetry results were obtained in 66 patients (87%) at a median of eight days after admittance and VFD were found in 52 cases (79%). Evaluation of VFD after six months revealed improvement in 52%. Patients with VFD had significantly lower composite score in VFQ-25 at both test points (77 vs. 96, p=0.001 and 87 vs. 97, p=0.009), in nine out of eleven subscales of VFQ-25 at 1 month and seven subscales after 6 months, including mental health, dependency, near and distance activities. Milder VFD had better results on VFQ-25 modifi