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Schwartz and Lellouch1 made an distinction between explanation-based studies, which confirm the physiological hypothesis or clinical hypothesis, as well as pragmatic trials, which inform the decision-making process for policy and practice. They also proposed the framework for pragmatic trials, which they called PRECIS.2 This tool attempted to define the characteristics of a pragmatic trial which includes the recruitment process, the design and implementation of the intervention, and follow-up. The number of pragmatic trials is growing. A recent Medline query that used the words pragmatic and naturalistic, which was restricted to randomised controlled trials (RCTs) returned 34 articles. These are highlighted in red on Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatic thinking. https://www.openlearning.com/u/camposburks-sjp6hu/blog/15TipsYourBossWishesYouKnewAboutPragmaticFreeSlotBuff is important to keep in mind, however, that the majority of studies were conducted in primary care settings.