https://www.selleckchem.com/products/Pancuronium-bromide(Pavulon).html ms at the gut, that can become apparent in a reduced fish performance. The need for fishmeal replacement by alternative ingredients such as plant sources to ensure the sustainability of the aquaculture sector has led the research assessing the intestinal status of fish to be of increasing importance. This scientific work provides further knowledge about the proteins and biologic processes altered in the gut in response to plant protein based diets, suggesting the loss of part of gut mucosa functionality. Nevertheless, the inclusion of alternative marine ingredients was able to reverse these negative effects, showing as a feasible option to develop sustainable aquafeeds. The incidence of severe filamentous fungi infections has increased over the past decade. Some of these filamentous fungi are resistant to available antifungals; it is thus urgent to find new compounds that are active against such life-threatening pathogens. Here, 1280 drugs (Prestwick Chemical Library) were tested against six multidrug-resistant filamentous fungi including, Aspergillus, Fusarium, Scedosporium, Rhizopus and Lichtheimia species. We identified several hits that induce fungal growth inhibition ≥ 70%. Clioquinol, alexidine dihydrochloride, hexachlorophene and thonzonium bromide, displayed a broad activity against all strains tested. This study enriches the potential antifungal options that can be used against multidrug-resistant invasive fungal diseases. BACKGROUND Linezolid is an antibiotic frequently used to treat vancomycin-resistant enterococcal infections. Vancomycin-susceptible Enterococcus faecalis can develop resistance to linezolid in environments with excessive linezolid use. AIM To define risk factors and outcome associated with the acquisition of linezolid-resistant Enterococcus faecalis. METHODS A retrospective study of cases and controls was designed involving patients hospitalized from January 2014 to Oc