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https://www.selleckchem.com/products/donafenib-sorafenib-d3.html Correlation between different CMR criteria varied from moderate to very strong. In multivariate binary logistic regression analysis with CMR and non-CMR parameters, independent positive predictors for a (L)PV were familial cardiomyopathy, trabecular mass, and meeting Petersen criteria in ≥2 out of 3 long axis views, while left bundle branch block and hypertension were negative predictors. The ROC-curve of this multivariate model had an area under the curve of 0.89 (95%CI 0.82-0.97). Conclusion CMR criteria together with family history help to distinguish those patients in whom a (L)PV can be identified, consequently leading to referral for genetic diagnostics and cascade screening.Objective This study aimed to identify outcome determinants for extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplantation (BTT) at our institution. Methods This retrospective single-center study reviewed patients on ECMO between 2010 and 2018 and compared clinical characteristics between patients who underwent successful-BTT and those who did not. Additionally, we examined differences between actively vs. emergently listed patients and reasons for failure-to-list. Results 76 patients were placed on ECMO with the intent to bridge to transplant. Of those, 42 were actively on the waitlist (AWL) prior to ECMO initiation, 20 were emergently evaluated and waitlisted (EWL) after ECMO initiation, and 14 failed-to-list. Of the 62 listed patients, 42 (68%) were successfully transplanted. Risk factors of failed-BTT included RV dysfunction prior to ECMO initiation, longer ECMO duration, reduced mobility status, shorter stature, higher prevalence of blood type B, worse kidney and liver function, and increased transfusion requirements. The number of patients transitioned to central VA-ECMO was higher in the failed-BTT group. Thirty-day survival post-transplantation was 98%, with 90% successfully discharged; 1-year surv

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